Although the undoubted achievements of modern current oncology, it remains one of the most important and current issues in medicine. The results achieved so far with regard to oncological diseases are still far from desirable for both patients and physicians.
More and more patients with cancer diseases, turn attention to the alternative medicine in their effort to fight suffering. At the basis of this interest is the desire to search for new perspectives to improve the results of traditional medicine, as well as their active participation in solving the healing problems. In most cases, oncology patients use alternative methods in parallel with traditional treatment methods, and their expectations are to reduce side effects from traditional treatment methods, prolong life, and improve immune function.
The definition alternative medicine includes a wide range of healing methods practiced and used instead of well-known methods in traditional medicines. The terminology “complementary medicine” (KAM) is specific and includes methods from alternative medicine, which are applied integrating with the healing methods of traditional medicines.
Recently, increasing popularity is gaining the term integrative oncology, which defines the synthesis between the best classical methods of treatment and scientifically confirmed complementary methods for the treatment of oncology diseases.
According to the definitions given by the National Center for alternative and complementary medicine (NCCAM) and National Cancer Institute (NCI) in USA, integrative oncology offers the following possibilities:
- Symptomatic treatment of the disease
- Improvement of the general conditions and quality of life for patients
- Improve the healing effectiveness
The usage of KAM in the treatment of oncology patients puts firm tendency for growth and it is a widely spread within the world.
Increasing popularity of KAM as well as the serious consequences of their uncontrolled applications is a reason in a number of countries that they are subject to serious state policy (for example National Center for alternative and complementary medicine in USA, NCCAM, Department for complementary and alternative medicine for cancer diseases to the National Health Institute in USA and etc). Leading academic medical centers around the world are developing a number of scientifically applicable programs in the field of integrative oncology.
A team of specialists from National Center of Infections and Disease- BulBio, Faculty of Pharmacy and Military Academy (Sofia) has been developing and examining for more than 25 years polybacterial oral immunostimulators (Respivax, Urostim, Dentavax, Respsim, etc.). Based on the numerous scientific data on the use of immunomodulators and nutraceutics in the integrative oncology and the great experience we have in creating multi-component immunomodulators, we have developed together with BulBio-NCIPD, “Fight against Cancer” Foundation and Hasumi-Bulgaria MIF:
- Immuno-Deoxy tablets – combined immunostimulator/antioxidant/micronutrient product.
- Pharinostim tablets, HepaFactor tablets; DeVox tablets, KlinoDetox tablets/powder products increasing tolerance to the therapy or decreasing some side effects.
- Immuno-Uro-Prostanorm tablets – immunomodulator of the prostate gland and urinary tract.
Low dosed polybacterial immunostimulator and specifically formulated complex composed from antioxidants, vitamins and microelements for supporting the immune, antioxidant and nutritional status:
- After conventional therapy for oncology dedeases
- In high risks patients with precancerous conditions, in remission, smoking and etc.
The creation of this new product is in collaboration with famous Bulgarian scientists such as academician Dr. B. Petrunov (long time director of NCIPD), Prof. I. Chernozemski (Chairman of the “Cancer Fighting Foundation”), Prof. Dr. Pl. Nenkov, former manager of BULBIO – NCSPP Ltd., Prof. Dr. M. Alyakov (Head of NMI on Radiation Protection at the Military Medical Academy, Sofia).
Due to the protective effect of such a combination, the data on its formulation were presented at an international oncology conference (Oncoprogress / Oncovaccines dated 29-30.10.2010, in Sofia) in the field of immune prophylaxis and immunotherapy of malignancies.
For more information – see attached leaflet.
Polybacterial immunostimulator for prophylaxis and treatment of the infectious disease of the upper respiratory tract.
Strong stimulator of the local mucous immunity in ears, nasal and throat infections and inflammatory conditions of the upper respiratory tract (prof Ivan Cenev and colleagues, ISUL hospital).
- acute and chronic pharyngitis, tonsillitis, sores, glossitis and stomatitis (including aphthous stomatitis), stomatomycosis;
- before and after operations and /or manipulations in the oral cavity and pharynx.
PHARINOSTIM LOZENGES IN ENT (EARS, NASAL AND TROAT) IN ONCOLOGY PRACTICE- CLINICAL OBSERVATION (K.Kirova, S.Neshkov, N. Petkov- UMBAL”Sveta Anna”Sofia, 2005)
31 patients with laryngeal carcinoma, tonsilata, tongue, hypopharynx and etc were observed with subsequent ray and chemotherapy;
Patients have different complaints – dry mouth, difficulty in swallowing, pain in swallowing, change in the mucosa of the mouth;
After the performed therapy:
- In 19 patients – very good results with almost complete disappearance of the complaints;
- In 7 patients – dryness significantly decreased, feeding without any difficulty;
- In 5 patients – no improvement was reported.
For more information – attached is a report from the clinical study from ass. Prof Petkov. Leaflet is attached as well.
It contains a patented silibin-phosphatidylcholine complex (Silifos®) with a five-fold increased intestinal resorption compared to regular silymarin. This innovative formula is actively studied in various liver diseases (US Patent 4764508).
Silifos® is the only clinically proven liver protector in hepatotoxic chemotherapy in children (Ladas et al, 2010 Jan 15; 116 (2): 506-13):
- Randomized, double-blind, placebo-controlled study of 50 children with acute lymphoblastic leukemia of maintenance chemotherapy and elevated liver enzymes;
- 24 children received Silifos® 5 mg /kg, 26 placebo-treated children;
- 28 days of supplementation, 56 days of follow-up.
On 56th day the active group had a significant lower AST values of (p=0, 05) with tendency for reduction of ALT (P=0.07).
Ladas EJ et al. A Randomized, Controlled, Double-Blind, Pilot Study of Milk Thistle for the Treatment of Hepatotoxicity in Childhood Acute Lymphoblastic Leukemia (ALL). Cancer. 2010 Jan 15;116(2):506-13.
DEVOX TABLETS (extract from Ginger)
Nausea and vomiting from a different origin
Dozens of clinical trials demonstrate the positive effect of preparations containing ginger powder or extracts in case of nausea and vomiting associated with pregnancy, operations, travelling. Despite the common use of conventional antiemetic products, a significant part of patients subjected to high emetogenna chemotherapy experiencing nausea and vomiting. This has encouraged several investigations with products on the basis of ginger, as the positive additive results to the standard therapy, placed it in the list of the most significant researches in the field of gynecological onco diseases in 2009 (price/efficacy).
Kim K, Ryu SY, Major clinical research advances in gynecologic cancer 2009. J Gynecol Oncol. 2009 Dec;20(4):203-9. Epub 2009 Dec 28. (attached)
Hickok JT et al. A Phase II/III Randomized, Placebo-Controlled, Double-Blind Clinical Trial of Ginger (Zingiber officinale) for Nausea Caused by Chemotherapy for Cancer: A Currently Accruing URCC CCOP Cancer Control Study. Support Cancer Ther. 2007 Sep 1;4(4):247-50.
CLINODETOX TABLETS/POWDER – micronized and lasting triboaktiviran natural clinoptilolite by KLS supersorbent-5.
Studies from many years of Bulgarian clinoptilolites from the White Bear, Beli Plast and Golobradovo fields in the Eastern Rhodopes region show the great opportunities of natural water-based aluminosilicates to adsorb ammonia compounds, heavy metals and radionuclides to strontium and cesium.
Studies of Bulgarian clinoptilolites from the White Bear, Beli Plast and Golobradovo troves in the Eastern Rhodopes show the great possibilities of natural water-based aluminosilicates to adsorb ammonia compounds, heavy metals and radionuclides to strontium and cesium. Studies conducted with farm animals (poultry, pigs, calves) fed with concentrated feeding stuff containing from 0.5 to 6% natural clinoptilolite confirm the world’s research into the great potential of clinoptilolites to support animal digestive processes by counteracting the toxic action of elevated levels of ammonia.
Extensive researches have been carried (in Bulgaria after Chernobil) by various teams on the possibilities of natural sorbents such as clays, bentonites and zeolites to play a role in soil, food and milk detoxifiers. Clinoptilolite as the most widespread zeolite mineral and its thermo-chemical modifiers have proven to be an effective means of protecting food and liquids from contamination with radioactive strontium and cesium.
In 2010-2011, ecotoxicological tests have been conducted within 90 days with a 90 number of white mice in 3 repetitions, fed with commercial feed for rodents containing 12.5% modified clinoptilolite – so called “KLS-10-MA” and water containing 0.5% of lead nitrate Pb (NO3) two show that clinoptilolite plays a highly detoxifying role in the digestive tract of mice. Mortality in test repetitions is decreased to 12-14% compared to 88-90% in the controls. Analysis of internal organs and the solid feces demonstrated that the lead component is disposed in the faeces
The developed clinoptilolite product “CLS-5” and its laboratory tests for the decontamination of lead, cadmium, strontium and cesium from liquid solutions have shown high efficiency due to the specific specific sorption, ion-exchange and catalytic properties of the mineral. This gave a reason to develop a nutritional supplement “Clinodetox” in a tablet form, in order to effectively support the normal detoxifying functions of the body by absorbing the harmful substances such as toxins, heavy metals and radionuclides taken with food.
Product data are presented at the scientific Cancer Conference “8th National Meeting with International participation of MIF Hasumi, Bulgaria, 2014”.
IMMUNO-URO-PROSTANORM TABLETS – immunomodulator of the prostate gland and urinary tract.